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by BlastRoom
What happens at the junction and inside the sarcomere when a muscle contracts.
#us_hs_anatomy_physiology
20 questions
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A nerve impulse reaches the synaptic knob and opens voltage-gated channels in its membrane. What moves into the knob next?
Calcium has entered the motor neuron terminal at the neuromuscular junction. What event follows immediately?
Acetylcholine has been released into the synaptic cleft. What is its next action?
Acetylcholine is bound to receptors on the motor end plate. What electrical change comes next in the muscle fiber?
The motor end plate reaches threshold and the electrical signal spreads over the sarcolemma. Which structure carries the signal deep into the fiber next?
Depolarization reaches the transverse tubules of a muscle fiber. Which organelle responds next to start contraction inside the sarcoplasm?
After the storage network releases calcium into the sarcoplasm, which protein binds those ions so the thin filament can expose attachment sites?
Calcium binds to troponin on the thin filament. What happens to the blocking strand that had covered cross-bridge attachment sites?
Calcium ions are pumped back into the sarcoplasmic reticulum after a twitch. What position do the regulatory proteins take on the thin filament?
In a relaxed sarcomere, which regulatory protein lies along actin and blocks cross-bridge attachment sites?
An action potential reaches the fiber, but calcium cannot bind troponin. What is the direct effect on the thin filament?
A myosin head has completed its power stroke and is still attached to actin. What must bind to the head so it releases?
ATPase activity splits ATP on a detached myosin head. What does that energy do to the head before the next pull?
A cocked myosin head binds actin while ADP and phosphate remain attached. What event starts the power stroke?
After the power stroke, ADP leaves the myosin head and no new ATP has bound yet. What is the state of the cross-bridge?
ATP detaches myosin heads and re-cocks them. Which other step needed for a muscle fiber to relax also uses ATP?
A toxin blocks acetylcholine receptors on the motor end plate. What happens to the muscle fiber served by that end plate?
Acetylcholinesterase in the synaptic cleft is inhibited after acetylcholine is released. What consequence follows at the end plate?
Calcium release channels in the sarcoplasmic reticulum fail to open during a muscle action potential. What follows inside the sarcomere?
A muscle fiber runs out of ATP while many myosin heads are attached to actin. What is the immediate effect on those heads?
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Major Muscles of the Head, Neck and Trunk
40 questions
